Large scale 3D CyCIF of thick tissue sections preserves intact cells, enabling accurate analysis of cell states, interactions, and spatially restricted signaling that thin sections miss.

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Detailed view of a blood vessel and cells in 3D CyCIF reveals intact cellular structures, interactions, and spatial organization within preserved tissue.

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3D mapping of human nephrons reveals glomerular communities connected by extensive nerve networks, coordinating kidney function and changing with development and disease.

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